Description

7-Chloro-1,3-Dihydro-2H-Imidazo[4,5-B]Pyridin-2-One is a high-value heterocyclic organic compound, identified by CAS NO 1202780-76-4, serving as a critical synthetic intermediate in modern pharmaceutical research and development. Its core value lies in its fused imidazopyridine scaffold, which is a privileged structure for designing bioactive molecules targeting various disease pathways. This compound is primarily needed by medicinal chemists and process development scientists within the pharmaceutical and biotechnology industries for the synthesis of novel drug candidates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential kinase inhibitors and other small-molecule therapeutics.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new active pharmaceutical ingredients (APIs).
• Chemical Biology Probes: Serves as a core scaffold for developing tool compounds to study biological pathways and target validation.
• Process Chemistry Development: Employed in route scouting and scale-up optimization for the commercial manufacturing of advanced pharmaceutical intermediates.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and development projects for global clients.

Basic Information

Product Name	7-Chloro-1,3-Dihydro-2H-Imidazo[4,5-B]Pyridin-2-One
CAS No.	1202780-76-4
Molecular Formula	C6H4ClN3O
Molecular Weight	169.57 g/mol
Synonyms	7-Chloro-2,3-dihydro-1H-imidazo[4,5-b]pyridin-2-one; 7-Chloro-1H-imidazo[4,5-b]pyridin-2(3H)-one; 7-Chloro-3H-imidazo[4,5-b]pyridin-2-one; 1202780-76-4; 7-Chloro-2,3-dihydroimidazo[4,5-b]pyridin-2-one; 7-Chloro-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one; 7-Chloro-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridine
EINECS	Contact for details

Quality Control

Our 7-Chloro-1,3-Dihydro-2H-Imidazo[4,5-B]Pyridin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.