Description

Imarikiren Hydrochloride is a high-purity, non-peptidic renin inhibitor used in pharmaceutical research and development. This compound is critical for investigating the renin-angiotensin system (RAS) pathway, a key target for managing hypertension and related cardiovascular conditions. It is primarily utilized by pharmaceutical companies, contract research organizations (CROs), and academic institutions engaged in cardiovascular drug discovery and preclinical studies.

Application

• Pharmaceutical R&D for cardiovascular disease therapeutics, specifically targeting hypertension.
• Lead Compound Optimization in the development of novel renin inhibitors.
• Biochemical Assays to study the mechanism of action and inhibition kinetics of renin.
• Preclinical Studies in animal models for pharmacokinetic and pharmacodynamic profiling.
• Reference Standard for analytical method development and validation in quality control laboratories.
• Academic Research into the pathophysiology of the renin-angiotensin-aldosterone system (RAAS).

Basic Information

Product Name	Imarikiren Hydrochloride
CAS No.	1202269-24-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Imarikiren HCl; Imarikiren Hydrochloride Salt; (2S,4S)-5-Biphenyl-4-yl-4-(3-carbamoyl-propylcarbamoyl)-2-methyl-pentanoic acid (2-methyl-1-oxo-1,2-dihydro-pyrido[3,4-b]pyrazin-7-ylmethyl)-amide hydrochloride; UNII-6R2J7Q6J7W; 6R2J7Q6J7W; SPP-1148 Hydrochloride
EINECS	Contact for details

Quality Control

Our Imarikiren Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets the stringent requirements for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specified standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.