Description

cis-2-Pyridin-3-Yl-Cyclopropanecarboxylic Acid CAS NO 1201922-23-7 is a high-purity, functionalized cyclopropane derivative featuring a pyridine moiety, serving as a critical chiral building block in advanced organic synthesis. This compound is valued for its rigid, three-membered ring structure which imparts unique conformational constraints, making it essential for modulating the biological activity and physicochemical properties of target molecules. It is primarily sought after by pharmaceutical and agrochemical research organizations for the development of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Synthesis: Used in constructing advanced intermediates for novel pesticides and herbicides, leveraging its structural rigidity for enhanced target binding.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes to study enzyme function and protein-ligand interactions.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific mechanical or electronic properties.

Basic Information

Product Name	cis-2-Pyridin-3-Yl-Cyclopropanecarboxylic Acid
CAS No.	1201922-23-7
Molecular Formula	C9H9NO2
Molecular Weight	163.17 g/mol
Synonyms	3-(2-Carboxycyclopropyl)pyridine; (1R,2S)-rel-2-(3-Pyridinyl)cyclopropanecarboxylic Acid; cis-2-(Pyridin-3-yl)cyclopropane-1-carboxylic Acid; 2-(3-Pyridyl)cyclopropanecarboxylic Acid; Cyclopropanecarboxylic acid, 2-(3-pyridinyl)-, cis-; 1201922-23-7; 3-Pyridinecyclopropanecarboxylic acid
EINECS	Contact for details

Quality Control

Our cis-2-Pyridin-3-Yl-Cyclopropanecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and development applications. Certificates of Analysis (COA) detailing purity, chiral purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is compatible with strong acids and organic solvents but should be kept separate from incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.