Description

Methyl 5-Cyano-3-Fluoropyridine-2-Carboxylate CAS NO 1200498-42-5 is a high-value, multi-functional heterocyclic building block featuring a cyano and a fluorine substituent on a pyridine core. This compound is critical for medicinal chemistry and advanced materials research, where its unique structure enables the synthesis of complex molecules with tailored properties. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for developing novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the development of kinase inhibitors, receptor antagonists, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis.
• Functional Material Research: Employed in the synthesis of organic electronic materials, such as those used in OLEDs or sensors.
• Chemical Biology Probes: Useful for constructing molecular probes to study biological processes and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A versatile starting material for bespoke chemical synthesis services.

Basic Information

Product Name	Methyl 5-Cyano-3-Fluoropyridine-2-Carboxylate
CAS No.	1200498-42-5
Molecular Formula	C8H5FN2O2
Molecular Weight	180.14 g/mol
Synonyms	Methyl 3-Fluoro-5-cyanopyridine-2-carboxylate; 2-Pyridinecarboxylic acid, 5-cyano-3-fluoro-, methyl ester; 5-Cyano-3-fluoropyridine-2-carboxylic acid methyl ester; 3-Fluoro-5-cyanopyridine-2-carboxylic acid methyl ester; Methyl 3-fluoro-5-cyanopicolinate; 1200498-42-5
EINECS	Contact for details

Quality Control

Our production of Methyl 5-Cyano-3-Fluoropyridine-2-Carboxylate adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.