Description

Methyl 5-Chloro-3-Fluoropyridine-2-Carboxylate is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique halogenated pyridine core structure makes it a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used as a precursor in the development of next-generation herbicides, fungicides, and insecticides with improved efficacy.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Building block for synthesizing functionalized polymers and advanced organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific molecule production.

Basic Information

Product Name	Methyl 5-Chloro-3-Fluoropyridine-2-Carboxylate
CAS No.	1200498-40-3
Molecular Formula	C7H5ClFNO2
Molecular Weight	189.57 g/mol
Synonyms	Methyl 5-chloro-3-fluoropyridine-2-carboxylate; 5-Chloro-3-fluoro-2-pyridinecarboxylic acid methyl ester; 2-Pyridinecarboxylic acid, 5-chloro-3-fluoro-, methyl ester; Methyl 5-chloro-3-fluoropicolinate; 5-Chloro-3-fluoropicolinic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 5-Chloro-3-Fluoropyridine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP standards where applicable, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.