Description

5-Carbamoyl-3-Chloropyridine-2-Carboxylic Acid is a high-purity pyridine derivative building block essential for advanced organic synthesis. Its bifunctional structure, featuring both a carboxylic acid and a carboxamide group on the chlorinated pyridine core, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated heterocyclic structure.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of functional polymers and organic electronic materials due to its rigid, aromatic backbone and reactive sites.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	5-Carbamoyl-3-Chloropyridine-2-Carboxylic Acid
CAS No.	1200497-79-5
Molecular Formula	C7H5ClN2O3
Molecular Weight	200.58 g/mol
Synonyms	3-Chloro-5-carbamoylpicolinic acid; 2-Pyridinecarboxylic acid, 5-carbamoyl-3-chloro-; 3-Chloro-5-aminocarbonylpyridine-2-carboxylic acid; 5-Carbamoyl-3-chloro-2-pyridinecarboxylic acid; 3-Chloro-5-cyanopyridine-2-carboxylic acid (hydrolyzed form); 5-Aminocarbonyl-3-chloropicolinic acid; 3-Chloropicolinamide-5-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 5-Carbamoyl-3-Chloropyridine-2-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.