Description

6-Bromo-5-Iodonicotinic Acid is a high-purity, multi-halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile, functionalized scaffold for constructing complex molecules, particularly in pharmaceutical and agrochemical research. This compound is essential for medicinal chemists and process development scientists engaged in creating novel active ingredients, where its specific halogen substitution pattern enables precise structural modifications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated nicotinic acid structure.
• Ligand Synthesis: Serves as a starting material for creating complex ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up processes in fine chemical production.
• Academic & Industrial R&D: Facilitates exploratory chemistry in academic institutions and corporate R&D centers for new compound libraries.

Basic Information

Product Name	6-Bromo-5-Iodonicotinic Acid
CAS No.	1200130-82-0
Molecular Formula	C6H3BrINO2
Molecular Weight	327.90 g/mol
Synonyms	5-Iodo-6-bromonicotinic acid; 6-Bromo-5-iodopyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 6-bromo-5-iodo-; 6-Bromo-5-iodo-3-pyridinecarboxylic acid; 6-Bromo-5-iodonicotinic acid; 1200130-82-0; Nicotinic acid, 6-bromo-5-iodo-
EINECS	Contact for details

Quality Control

Our 6-Bromo-5-Iodonicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.