Description

1H-Pyrrolo[2,3-B]Pyridine-3-Carboxylic Acid, 5-Bromo-2-(Bromomethyl)-1-(Phenylsulfonyl)-, Methyl Ester is a high-purity, multi-functionalized heterocyclic building block of significant interest in advanced organic synthesis. Its complex molecular architecture, featuring bromomethyl and phenylsulfonyl protecting groups, makes it a critical intermediate for constructing novel pharmacologically active scaffolds. This compound is primarily sought after by pharmaceutical R&D organizations and fine chemical manufacturers engaged in the development of kinase inhibitors and other targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for oncology and antiviral research.
• Kinase Inhibitor Development: Serves as a core scaffold for designing and synthesizing potent and selective kinase inhibitors due to its pyrrolopyridine structure.
• Chemical Biology Probes: Used in medicinal chemistry to create tool compounds for studying biological pathways and target validation.
• Custom Synthesis Building Block: Employed in contract research and manufacturing (CRO/CMO) for bespoke, multi-step synthetic routes.
• Agrochemical Research: Potential intermediate in the development of new active ingredients with specific biological activity.
• Material Science Exploration: Investigated for creating novel organic electronic materials or ligands for catalytic systems.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-3-Carboxylic Acid, 5-Bromo-2-(Bromomethyl)-1-(Phenylsulfonyl)-, Methyl Ester
CAS No.	1200130-73-9
Molecular Formula	C16H12Br2N2O4S
Molecular Weight	488.15 g/mol
Synonyms	5-Bromo-2-(bromomethyl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid methyl ester; Methyl 5-bromo-2-(bromomethyl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxylate; 1-Tosyl-5-bromo-2-bromomethyl-7-azaindole-3-carboxylic acid methyl ester; 1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid, 5-bromo-2-(bromomethyl)-1-(phenylsulfonyl)-, methyl ester; 7-Azaindole-3-carboxylic acid derivative; Pyrrolopyridine sulfonamide ester.
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced under strict quality management systems. We employ state-of-the-art analytical techniques, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all critical specifications is provided with each shipment, supporting your regulatory and R&D documentation needs. Our commitment to cGMP principles ensures reliable supply for pre-clinical and clinical-stage development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed in a dry environment to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference material
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.