Description

4-(3-Bromo-5-Chloropyridin-2-Yl)Morpholine is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound is critical for medicinal chemistry and agrochemical research, serving as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and crop protection agents. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce complex morpholine and halogenated pyridine motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing potential drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Material Science Research: Serves as a precursor for creating functionalized ligands and complex organic frameworks for catalytic and electronic applications.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis projects requiring precise functionalization on the pyridine ring.
• Academic & Industrial R&D: Employed in discovery chemistry for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	4-(3-Bromo-5-Chloropyridin-2-Yl)Morpholine
CAS No.	1199773-36-8
Molecular Formula	C9H10BrClN2O
Molecular Weight	277.55 g/mol
Synonyms	2-Morpholino-3-bromo-5-chloropyridine; 3-Bromo-5-chloro-2-morpholinopyridine; 4-(3-Bromo-5-chloro-2-pyridinyl)morpholine; Morpholine, 4-(3-bromo-5-chloro-2-pyridinyl)-; 1199773-36-8; 3-Bromo-5-chloro-2-(morpholin-4-yl)pyridine
EINECS	Contact for details

Quality Control

Our 4-(3-Bromo-5-Chloropyridin-2-Yl)Morpholine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥97.0% (Area Percent)
Related Substances (HPLC)	Total impurities ≤3.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.