Description

Carbamic Acid, n-(6-Chloro-2-Formyl-3-Pyridinyl)-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its specific pyridine and carbamate functional groups. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) where precise molecular architecture is required. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities with improved efficacy and safety profiles.
• Process Chemistry Development: Serves as a critical starting material or intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Agrochemical Synthesis: Potential application as an intermediate in the development of advanced crop protection agents and pesticides.
• Chemical Biology Probes: Can be utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	Carbamic Acid, n-(6-Chloro-2-Formyl-3-Pyridinyl)-, 1,1-Dimethylethyl Ester
CAS No.	1199557-04-4
Molecular Formula	C11H13ClN2O3
Molecular Weight	256.69 g/mol
Synonyms	tert-Butyl (6-chloro-2-formylpyridin-3-yl)carbamate; N-(6-Chloro-2-formyl-3-pyridinyl)carbamic Acid 1,1-Dimethylethyl Ester; 3-((tert-Butoxycarbonyl)amino)-6-chloropicolinaldehyde; 6-Chloro-3-((tert-butoxycarbonyl)amino)picolinaldehyde; BOC-Protected 3-Amino-6-chloropicolinaldehyde; (6-Chloro-2-formylpyridin-3-yl)carbamic Acid tert-Butyl Ester
EINECS	Contact for details

Quality Control

Our Carbamic Acid, n-(6-Chloro-2-Formyl-3-Pyridinyl)-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques including HPLC, GC, and NMR. We adhere to ICH guidelines for stability and impurity characterization, ensuring the material meets the stringent requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if specified. Keep away from incompatible materials such as strong acids and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.