Description

Esomeprazole (Magnesium Salt) CAS NO 1198768-91-0 is the magnesium salt form of the S-isomer of omeprazole, representing a high-purity active pharmaceutical ingredient (API). This compound is a proton pump inhibitor (PPI) that offers superior control over gastric acid secretion for therapeutic applications. It is essential for pharmaceutical manufacturers developing advanced treatments for acid-related gastrointestinal disorders, including gastroesophageal reflux disease (GERD) and peptic ulcers.

Application

• Primary Active Pharmaceutical Ingredient (API) in prescription medications for acid suppression.
• Formulation of delayed-release capsules and tablets for the treatment of GERD.
• Manufacturing of combination therapies for Helicobacter pylori eradication.
• Production of intravenous (IV) formulations for hospitalized patients unable to take oral medication.
• Research and development of novel drug delivery systems for improved bioavailability.
• Reference standard in analytical laboratories for quality control and method validation.

Basic Information

Product Name	Esomeprazole (Magnesium Salt)
CAS No.	1198768-91-0
Molecular Formula	C34H36MgN6O6S2
Molecular Weight	713.12 g/mol
Synonyms	Esomeprazole Magnesium; (S)-Omeprazole Magnesium; Esomeprazole Magnesium Trihydrate; Nexium® (Brand Name); Perprazole; H 199/18; E 3810; Magnesium bis(5-methoxy-2-[(S)-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl]-1H-benzimidazol-1-ide)
EINECS	Contact for details

Quality Control

Our Esomeprazole Magnesium is manufactured under strict quality management systems. It is produced to meet the stringent requirements of major pharmacopoeias, including USP and EP monographs. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White or almost white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.