Description

Ethyl 5-Chloro-3-(Trifluoromethyl)-2-Pyridinecarboxylate is a high-value pyridine derivative and a key synthetic intermediate in advanced organic chemistry. This compound is prized for its trifluoromethyl and chloro substituents, which are critical for modulating the biological activity and physicochemical properties of target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) agents, anti-infectives, and oncology drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Material Science Research: Serves as a precursor for the development of specialty chemicals, liquid crystals, and functionalized ligands for catalytic systems.
• Custom Synthesis & Contract Manufacturing: An essential substrate for fine chemical manufacturers and CDMOs (Contract Development and Manufacturing Organizations) engaged in custom synthesis projects.

Basic Information

Product Name	Ethyl 5-Chloro-3-(Trifluoromethyl)-2-Pyridinecarboxylate
CAS No.	1198475-50-1
Molecular Formula	C9H7ClF3NO2
Molecular Weight	253.60 g/mol
Synonyms	Ethyl 5-chloro-3-(trifluoromethyl)picolinate; 5-Chloro-3-(trifluoromethyl)picolinic acid ethyl ester; 2-Pyridinecarboxylic acid, 5-chloro-3-(trifluoromethyl)-, ethyl ester; Ethyl 5-chloro-3-(trifluoromethyl)pyridine-2-carboxylate; 1198475-50-1; ETCTP
EINECS	Contact for details

Quality Control

Our Ethyl 5-Chloro-3-(Trifluoromethyl)-2-Pyridinecarboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.