Description

Methyl 6-Amino-1H-Pyrrolo[3,2-B]Pyridine-2-Carboxylate CAS NO 1198420-91-5 is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyrrolopyridine class of heterocyclic compounds. This compound is a critical building block in modern medicinal chemistry, valued for its unique scaffold which is integral to the synthesis of novel bioactive molecules. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of small-molecule drug candidates targeting various disease pathways.
• Oncology Research: Used to construct kinase inhibitors and other targeted cancer therapies due to its privileged heterocyclic structure.
• CNS Drug Development: Serves as a core scaffold for compounds designed to cross the blood-brain barrier for treating neurological disorders.
• Chemical Biology & Proteomics: Employed in the design of molecular probes and tool compounds for studying protein function and cellular mechanisms.
• Agrochemical Research: Potential application in developing novel active ingredients for crop protection.
• Academic & Contract Research: Essential for synthetic chemistry research and custom synthesis projects in academic and CRO (Contract Research Organization) settings.

Basic Information

Product Name	Methyl 6-Amino-1H-Pyrrolo[3,2-B]Pyridine-2-Carboxylate
CAS No.	1198420-91-5
Molecular Formula	C9H9N3O2
Molecular Weight	191.19 g/mol
Synonyms	6-Amino-1H-pyrrolo[3,2-b]pyridine-2-carboxylic acid methyl ester; Methyl 6-amino-1H-pyrrolo[3,2-b]pyridine-2-carboxylate; 1H-Pyrrolo[3,2-b]pyridine-2-carboxylic acid, 6-amino-, methyl ester; 6-Amino-1H-pyrrolo[3,2-b]pyridine-2-carboxylic acid methyl ester; Methyl 6-aminopyrrolo[3,2-b]pyridine-2-carboxylate; 1198420-91-5; 6-Amino-1H-pyrrolo[3,2-b]pyridine-2-methyl carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 6-Amino-1H-Pyrrolo[3,2-B]Pyridine-2-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for research and development applications. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.