Description

4-(2-Bromophenyl)Piperidine Hydrochloride is a high-purity, advanced pharmaceutical intermediate and versatile organic building block. This compound is critical for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for synthesizing complex molecules with potential therapeutic applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of novel crop protection agents and pesticides.
• Ligand and Catalyst Development: Acts as a building block for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and protein functions.
• Academic & Institutional R&D: Essential for fundamental organic synthesis research and the development of new synthetic methodologies in university and institutional laboratories.

Basic Information

Product Name	4-(2-Bromophenyl)Piperidine Hydrochloride
CAS No.	1198285-51-6
Molecular Formula	C11H14BrClN
Molecular Weight	276.59 g/mol
Synonyms	4-(2-Bromophenyl)piperidine HCl; 4-(2-Bromophenyl)piperidine hydrochloride; 2-Bromo-4-piperidinobenzene hydrochloride; 1-(2-Bromophenyl)-4-piperidinol hydrochloride (tautomer); Piperidine, 4-(2-bromophenyl)-, hydrochloride; 4-(o-Bromophenyl)piperidine hydrochloride; 4-(2-Bromo-phenyl)-piperidine hydrochloride; 4-(2-Bromophenyl)piperidine, HCl salt
EINECS	Contact for details

Quality Control

Every batch of 4-(2-Bromophenyl)Piperidine Hydrochloride is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay, impurity profiles, and residual solvents. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity	≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.