Description

6-Chloronicotinimidamide Dihydrochloride is a high-purity chemical intermediate of significant importance in modern organic synthesis. This compound matters for its role as a versatile building block in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the nicotinamide scaffold for biological activity.
• Chemical Research & Development: Serves as a critical building block in academic and industrial R&D for exploring new chemical entities and reaction pathways.
• Ligand and Catalyst Preparation: Employed in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions, which are fundamental in fine chemical manufacturing.

Basic Information

Product Name	6-Chloronicotinimidamide Dihydrochloride
CAS No.	1198283-62-3
Molecular Formula	C6H7ClN3·2HCl
Molecular Weight	237.96 g/mol
Synonyms	6-Chloropyridine-3-carboximidamide dihydrochloride; 3-Pyridinecarboximidamide, 6-chloro-, dihydrochloride; 6-Chloro-3-pyridinecarboximidamide dihydrochloride; 6-Chloronicotinamidine dihydrochloride; 6-Chloro-3-cyanopyridine dihydrochloride (related precursor); 6-Chloro-3-carbamimidoylpyridine dihydrochloride
EINECS	Contact for details

Quality Control

Our 6-Chloronicotinimidamide Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic intermediates. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.