Description

(E)-5-Methyl-1H-Pyrrolo[2,3-B]Pyridine-3-Carbaldehyde Oxime CAS NO 1198098-52-0 is a high-purity, advanced pharmaceutical intermediate characterized by its specific oxime functional group and fused heterocyclic structure. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of novel, targeted therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel drug candidates, particularly in oncology and inflammatory disease pathways.
• Kinase Inhibitor Synthesis: Serves as a core scaffold for constructing potent and selective kinase inhibitors, targeting specific enzymes involved in cell signaling.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization to improve drug potency, selectivity, and pharmacokinetic properties.
• Bioconjugation & Probe Development: The oxime group can be utilized for site-specific bioconjugation, enabling the creation of chemical probes for biological target identification and validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical companies with custom synthesis and scale-up services.

Basic Information

Product Name	(E)-5-Methyl-1H-Pyrrolo[2,3-B]Pyridine-3-Carbaldehyde Oxime
CAS No.	1198098-52-0
Molecular Formula	C10H9N3O
Molecular Weight	187.20 g/mol
Synonyms	(E)-5-Methyl-1H-pyrrolo[2,3-b]pyridine-3-carboxaldehyde oxime; 5-Methyl-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde oxime; 1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 5-methyl-, oxime; 5-Methyl-7-azaindole-3-carboxaldehyde oxime; (E)-5-Methyl-7-azaindole-3-carbaldehyde oxime; 5-Methyl-1H-pyrrolo[2,3-b]pyridin-3-carbaldehyde oxime
EINECS	Contact for details

Quality Control

Our (E)-5-Methyl-1H-Pyrrolo[2,3-B]Pyridine-3-Carbaldehyde Oxime is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.