Description

5-Bromo-7-Chloro-1-(Triisopropylsilyl)-1H-Pyrrolo[2,3-C]Pyridine is a high-value, multi-functionalized pyrrolopyridine derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in providing a protected, halogenated scaffold that enables precise downstream functionalization for the development of novel bioactive molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for use in medicinal chemistry, process development, and the synthesis of complex heterocyclic libraries.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly kinase inhibitors and other small-molecule therapeutics targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization campaigns due to its versatile halogen handles (bromo and chloro) for cross-coupling reactions.
• Agrochemical Development: Serves as a precursor in the research and synthesis of novel pesticides, herbicides, or fungicides containing the pyrrolopyridine core.
• Chemical Biology Probes: Utilized in the design and creation of molecular probes for studying biological processes and target validation.
• Material Science Research: Potential intermediate for the development of organic electronic materials or ligands for catalytic systems, leveraging its electron-rich heterocyclic structure.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific, high-purity advanced intermediate.

Basic Information

Product Name	5-Bromo-7-Chloro-1-(Triisopropylsilyl)-1H-Pyrrolo[2,3-C]Pyridine
CAS No.	1198096-80-8
Molecular Formula	C17H26BrClN2Si
Molecular Weight	401.84 g/mol
Synonyms	1H-Pyrrolo[2,3-c]pyridine, 5-bromo-7-chloro-1-[(1,1-dimethylethyl)dimethylsilyl]-; 5-Bromo-7-chloro-1-[(1,1-dimethylethyl)dimethylsilyl]-1H-pyrrolo[2,3-c]pyridine; 5-Bromo-7-chloro-1-(tert-butyldimethylsilyl)-1H-pyrrolo[2,3-c]pyridine (common error/alternative); TIPS-protected 5-bromo-7-chloropyrrolopyridine; 5-Br-7-Cl-1-TIPS-pyrrolo[2,3-c]pyridine
EINECS	Contact for details

Quality Control

Our 5-Bromo-7-Chloro-1-(Triisopropylsilyl)-1H-Pyrrolo[2,3-C]Pyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.