Description

Ap26113 CAS NO 1197958-12-5 is a high-purity, small molecule chemical compound of significant interest in advanced research and development. This compound serves as a critical intermediate or active component in the synthesis of novel therapeutic agents, particularly within the field of targeted oncology. It is primarily sought after by pharmaceutical R&D departments, biotechnology firms, and academic research institutions engaged in drug discovery programs. The material's specific properties make it essential for investigating new pathways and developing next-generation treatments.

Application

• Pharmaceutical Research & Development: As a key intermediate or reference standard in the synthesis and optimization of novel drug candidates, especially for targeted cancer therapies.
• Biochemical Assay Development: Utilized as a precise tool compound or inhibitor in high-throughput screening (HTS) and mechanism-of-action studies to validate new biological targets.
• Preclinical Studies: Serves as a critical material for in vitro and in vivo pharmacological testing to establish efficacy and safety profiles of new chemical entities.
• Academic Research: Used in university and institutional labs for fundamental research in medicinal chemistry, signal transduction, and disease biology.
• Contract Research Organizations (CROs): Employed as a reliable, high-quality material for client-sponsored drug discovery and development projects.
• Process Chemistry & Scale-Up: Acts as a benchmark for developing and optimizing robust, scalable synthetic routes for potential Active Pharmaceutical Ingredients (APIs).

Basic Information

Product Name	Ap26113
CAS No.	1197958-12-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	AP-26113; Brigatinib (common name); ALUNBRIG (trade name); 5-Chloro-N4-[2-(dimethylphosphoryl)phenyl]-N2-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]pyrimidine-2,4-diamine; UNII-6KQ9WZ5F8I
EINECS	Contact for details

Quality Control

Our Ap26113 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. The product undergoes rigorous analytical testing, including HPLC for purity determination and spectroscopic methods for structural confirmation. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each batch to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.