Description

tert-Butyl 4-(4-Bromopyridin-2-yl)piperazine-1-carboxylate is a high-value, protected piperazine derivative featuring a bromopyridine moiety, serving as a critical synthetic intermediate in modern organic chemistry. This compound is essential for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought after by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, especially in kinase inhibitor and central nervous system (CNS) active compound libraries.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its versatile piperazine core and halogen handle for further functionalization.
• Agrochemical Synthesis: Employed in the development of novel herbicides, fungicides, and insecticides that require complex heterocyclic scaffolds.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Material Science: Acts as a precursor for specialty polymers or ligands used in catalysis and advanced material applications.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	tert-Butyl 4-(4-Bromopyridin-2-yl)piperazine-1-carboxylate
CAS No.	1197294-80-6
Molecular Formula	C14H20BrN3O2
Molecular Weight	342.23 g/mol
Synonyms	1-Boc-4-(4-bromopyridin-2-yl)piperazine; tert-Butyl 4-(4-bromo-2-pyridinyl)-1-piperazinecarboxylate; 4-(4-Bromopyridin-2-yl)piperazine-1-carboxylic acid tert-butyl ester; 2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)-4-bromopyridine; N-Boc-4-(4-bromopyridin-2-yl)piperazine; BOC-4-(4-Bromo-2-pyridyl)piperazine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(4-Bromopyridin-2-yl)piperazine-1-carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific project requirements, including those for research and cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.