Description

1H-Pyrrolo[2,3-B]Pyridine-5-Carbonyl Chloride is a high-value heterocyclic building block and key synthetic intermediate. This compound is critical for the efficient construction of complex molecular architectures, particularly in advanced pharmaceutical research and development. It is primarily sought after by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides with specific modes of action.
• Material Science: Serves as a precursor for organic electronic materials, such as those used in OLEDs and semiconductors.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for biological target validation.
• Custom Synthesis: A key starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.
• Academic Research: Utilized in university and institutional labs for methodological development and exploratory synthesis of new chemical entities.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-5-Carbonyl Chloride
CAS No.	1196987-68-4
Molecular Formula	C9H5ClN2O
Molecular Weight	192.60 g/mol
Synonyms	5-Carboxy-7-azaindole chloride; 7-Azaindole-5-carbonyl chloride; 1H-Pyrrolo[2,3-b]pyridine-5-carboxylic acid chloride; 5-Chlorocarbonyl-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine-5-carbonyl chloride; 7-Aza-1H-indole-5-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-5-Carbonyl Chloride is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.