Description

2-Amino-6-Bromonicotinic Acid is a high-value brominated nicotinic acid derivative, serving as a critical building block in modern synthetic chemistry. Its primary commercial value lies in its dual functional groups, which enable its use as a versatile intermediate for constructing complex heterocyclic scaffolds. This compound is essential for research and development laboratories and production facilities in the pharmaceutical and agrochemical sectors, where it is utilized in the synthesis of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides and insecticides, leveraging its bromine atom for further functionalization.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions, such as Suzuki and Buchwald-Hartwig aminations.
• Material Science Research: Acts as a monomer or functionalizing agent in the creation of organic electronic materials and advanced polymers.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: Serves as a starting material for custom synthesis projects and scale-up processes under cGMP conditions.

Basic Information

Product Name	2-Amino-6-Bromonicotinic Acid
CAS No.	1196157-51-3
Molecular Formula	C6H5BrN2O2
Molecular Weight	217.02 g/mol
Synonyms	6-Bromo-2-aminonicotinic acid; 2-Amino-6-bromopyridine-3-carboxylic acid; 3-Carboxy-6-bromo-2-aminopyridine; 6-Bromo-2-aminopyridine-3-carboxylic acid; 2-Amino-6-bromo-3-pyridinecarboxylic acid; Nicotinic acid, 2-amino-6-bromo-; 1196157-51-3
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-6-Bromonicotinic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.