Description

4-Ethynylpyridin-3-Amine is a versatile pyridine derivative featuring both an amine and an ethynyl functional group, making it a valuable bifunctional building block in advanced organic synthesis. Its molecular structure is critical for constructing complex heterocyclic frameworks and functionalized ligands. This compound is primarily sought after by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in developing novel pesticides and herbicides by serving as a core scaffold for bioactive molecules.
• Ligand Synthesis: Acts as a versatile starting material for creating specialized ligands in catalysis and coordination chemistry.
• Material Science: Building block for synthesizing conjugated polymers and organic electronic materials due to its ethynyl group.
• Chemical Biology: Useful in probe and linker synthesis for bioconjugation and activity-based protein profiling.
• Academic & R&D: Fundamental research reagent for exploring new organic reactions and heterocyclic chemistry.

Basic Information

Product Name	4-Ethynylpyridin-3-Amine
CAS No.	1196156-75-8
Molecular Formula	C7H6N2
Molecular Weight	118.14 g/mol
Synonyms	3-Amino-4-ethynylpyridine; 4-Ethynyl-3-pyridinamine; 4-Ethynylpyridin-3-ylamine; 3-Pyridinamine, 4-ethynyl-; 4-Ethynyl-3-aminopyridine
EINECS	Contact for details

Quality Control

Our 4-Ethynylpyridin-3-Amine is manufactured under strict quality protocols to ensure high purity and batch-to-batch consistency. Each lot undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all specifications and test results to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.