Description

2-Chloro-5,6,7,8-Tetrahydro-Pyrido[3,4-D]Pyrimidine is a high-value heterocyclic building block and key synthetic intermediate. This compound matters for its crucial role in constructing complex molecular architectures, particularly in medicinal chemistry. Pharmaceutical R&D and fine chemical synthesis teams need it for developing new active pharmaceutical ingredients (APIs) and other advanced organic compounds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in structure-activity relationship (SAR) studies and lead optimization.
• Organic Synthesis Building Block: Used in the preparation of more complex pyrido[3,4-d]pyrimidine derivatives and fused heterocyclic systems.
• Agrochemical Development: Potential intermediate in the research and synthesis of novel crop protection agents and pesticides.
• Chemical Biology Probes: Can be utilized to create molecular probes for studying biological pathways and enzyme functions.
• Contract Manufacturing (CMO): Supplied to custom synthesis and contract manufacturing organizations for cGMP and non-GMP production runs.

Basic Information

Item	Details
Product Name	2-Chloro-5,6,7,8-Tetrahydro-Pyrido[3,4-D]Pyrimidine
CAS No.	1196153-06-6
Molecular Formula	C7H8ClN3
Molecular Weight	169.61 g/mol
Synonyms	2-Chloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine; 2-Chloro-5,6,7,8-tetrahydro-1H-pyrido[3,4-d]pyrimidine; 2-Chloro-5,6,7,8-tetrahydro-pyrido[3,4-d]pyrimidine; 1196153-06-6; Pyrido[3,4-d]pyrimidine, 2-chloro-5,6,7,8-tetrahydro-; 2-Chloro-5,6,7,8-tetrahydro-1,6-naphthyridine; 2-Chloro-5,6,7,8-tetrahydro-1H-1,6-naphthyridine
EINECS	Contact for details

Quality Control

Our 2-Chloro-5,6,7,8-Tetrahydro-Pyrido[3,4-D]Pyrimidine is manufactured under strict quality management systems. We offer material suitable for research and development, with higher purity grades available for advanced applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Higher grades available)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.