Description

4-Bromo-2-Chloro-6-Methoxypyridine is a high-purity halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a versatile intermediate for constructing complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), crop protection agents, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides requiring specific halogenated pyridine cores.
• Material Science: Serves as a precursor for ligands in catalysis and for creating functionalized polymers or liquid crystals.
• Chemical Research: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the bromo-chloro-methoxypyridine moiety into target molecules.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs developing custom chemical entities for clients.

Basic Information

Product Name	4-Bromo-2-Chloro-6-Methoxypyridine
CAS No.	1196152-02-9
Molecular Formula	C6H5BrClNO
Molecular Weight	222.46 g/mol
Synonyms	2-Chloro-4-bromo-6-methoxypyridine; 6-Methoxy-2-chloro-4-bromopyridine; 4-Bromo-2-chloro-6-methoxypyridine; 2-Chloro-6-methoxy-4-bromopyridine; Pyridine, 4-bromo-2-chloro-6-methoxy-; 1196152-02-9
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Chloro-6-Methoxypyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.