Description

tert-Butyl 2-Formylpyridin-4-Ylcarbamate is a high-purity, advanced pharmaceutical intermediate characterized by its reactive aldehyde and protected carbamate functionalities. This compound matters as a critical building block for the synthesis of complex molecules, enabling the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for drug discovery and process development programs.

Application

• Pharmaceutical Intermediate: A key synthon for constructing heterocyclic compounds and complex molecular scaffolds in medicinal chemistry.
• API Synthesis: Serves as a versatile precursor in the multi-step synthesis of potential drug candidates, particularly those targeting neurological and oncological pathways.
• Chemical Research: Used in academic and industrial R&D for exploring new synthetic methodologies and creating libraries of novel compounds for screening.
• Agrochemical Development: Employed in the research and synthesis of new active ingredients for crop protection products.
• Ligand and Catalyst Preparation: Useful for the synthesis of specialized ligands and organocatalysts due to its formyl and pyridine groups.

Basic Information

Product Name	tert-Butyl 2-Formylpyridin-4-Ylcarbamate
CAS No.	1196151-92-4
Molecular Formula	C11H14N2O3
Molecular Weight	222.24 g/mol
Synonyms	4-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-pyridinecarboxaldehyde; 2-Formylpyridin-4-ylcarbamic acid tert-butyl ester; tert-Butyl N-(2-formylpyridin-4-yl)carbamate; 4-(tert-Butoxycarbonylamino)picolinaldehyde; Boc-4-amino-2-picolinaldehyde; 4-(Boc-amino)-2-pyridinecarboxaldehyde; 4-N-Boc-amino-2-formylpyridine
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Formylpyridin-4-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C or as specified on the Certificate of Analysis. Due to its sensitivity to oxidation, the container should be purged with inert gas after each opening to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.