Description

Methyl 4-Ethynylpyridine-2-Carboxylate is a high-value pyridine derivative and a versatile building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of pharmaceuticals, agrochemicals, and functional materials, enabling the construction of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and ligands.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its pyridine core for biological activity.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organometallic chemistry.
• Material Science: Employed in the synthesis of organic electronic materials, conductive polymers, and metal-organic frameworks (MOFs).
• Chemical Research: A valuable reagent for academic and industrial research in heterocyclic and medicinal chemistry.
• Fine Chemical Production: Integrated into multi-step syntheses for producing high-value specialty chemicals.

Basic Information

Product Name	Methyl 4-Ethynylpyridine-2-Carboxylate
CAS No.	1196151-91-3
Molecular Formula	C9H7NO2
Molecular Weight	161.16 g/mol
Synonyms	Methyl 4-ethynylpicolinate; 2-Pyridinecarboxylic acid, 4-ethynyl-, methyl ester; 4-Ethynylpyridine-2-carboxylic acid methyl ester; Methyl 4-ethynyl-2-pyridinecarboxylate; 4-Ethynylpicolinic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 4-Ethynylpyridine-2-Carboxylate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.