Description

3-Bromo-5H,6H,7H-Cyclopenta[B]Pyridin-5-Amine is a high-purity, advanced pharmaceutical intermediate characterized by its fused cyclopentapyridine core structure. This compound is of significant value for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel drug candidates. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on creating new therapeutic agents, particularly in areas requiring complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) targeting various therapeutic areas.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies to develop new drug candidates.
• Chemical Biology Probes: Serves as a core structure for developing molecular probes to study biological pathways and protein function.
• Agrochemical Synthesis: Potential intermediate in the development of novel pesticides or herbicides requiring specific heterocyclic activity.
• Material Science Precursor: Can be utilized in the synthesis of organic electronic materials or ligands for catalytic systems.

Basic Information

Product Name	3-Bromo-5H,6H,7H-Cyclopenta[B]Pyridin-5-Amine
CAS No.	1196151-64-0
Molecular Formula	C8H9BrN2
Molecular Weight	213.07 g/mol
Synonyms	3-Bromo-5H,6H,7H-cyclopenta[b]pyridin-5-amine; 5-Amino-3-bromo-5H,6H,7H-cyclopenta[b]pyridine; 3-Bromo-5-amino-6,7-dihydro-5H-cyclopenta[b]pyridine; 3-Bromo-5-aminocyclopenta[b]pyridine; 5H,6H,7H-Cyclopenta[b]pyridin-5-amine, 3-bromo-; 3-Bromo-6,7-dihydro-5H-cyclopenta[b]pyridin-5-amine
EINECS	Contact for details

Quality Control

Our 3-Bromo-5H,6H,7H-Cyclopenta[B]Pyridin-5-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.