Description

6H-Pyrrolo[2,3-C]Pyridine-6-Carboxylic Acid, Octahydro-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new drugs, especially within oncology and central nervous system (CNS) research.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates and novel APIs.
• Organic Synthesis Building Block: Used in research and development for constructing fused pyrrolopyridine scaffolds, which are privileged structures in medicinal chemistry.
• Drug Discovery & Development: Serves as a versatile starting material for creating compound libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and the exploration of new chemical entities.
• Process Chemistry: Used in the scale-up and optimization of synthetic routes for potential clinical trial materials.

Basic Information

Item	Detail
Product Name	6H-Pyrrolo[2,3-C]Pyridine-6-Carboxylic Acid, Octahydro-, 1,1-Dimethylethyl Ester
CAS No.	1196147-27-9
Molecular Formula	C14H24N2O2
Molecular Weight	252.35 g/mol
Synonyms	tert-Butyl octahydro-6H-pyrrolo[2,3-c]pyridine-6-carboxylate; 6H-Pyrrolo[2,3-c]pyridine-6-carboxylic acid, octahydro-, 1,1-dimethylethyl ester; Octahydro-6H-pyrrolo[2,3-c]pyridine-6-carboxylic acid tert-butyl ester; Boc-protected octahydropyrrolo[2,3-c]pyridine; tert-Butyl 2,3,3a,4,5,6,7,7a-octahydro-1H-pyrrolo[2,3-c]pyridine-6-carboxylate
EINECS	Contact for details

Quality Control

Our 6H-Pyrrolo[2,3-C]Pyridine-6-Carboxylic Acid, Octahydro-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in its original packaging to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.