Description

5-Bromo-2-Chloro-4-Hydroxypyridine is a halogenated pyridine derivative that serves as a versatile and high-value synthetic intermediate in advanced organic chemistry. Its unique substitution pattern makes it a critical building block for constructing complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), agrochemicals, and functional materials who require reliable access to high-purity, structurally defined intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, leveraging its halogenated pyridine core.
• Material Science Research: Serves as a building block for creating functional organic molecules used in electronic materials, ligands for catalysis, and liquid crystals.
• Chemical Biology & Proteomics: Employed as a molecular scaffold or tagging reagent in the design of chemical probes and activity-based protein profiling (ABPP) agents.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	5-Bromo-2-Chloro-4-Hydroxypyridine
CAS No.	1196146-82-3
Molecular Formula	C5H3BrClNO
Molecular Weight	208.44 g/mol
Synonyms	4-Hydroxy-5-bromo-2-chloropyridine; 2-Chloro-5-bromo-4-pyridinol; 5-Bromo-2-chloro-4-pyridone; 2-Chloro-5-bromo-4-hydroxypyridine; 4-Pyridinol, 5-bromo-2-chloro-; 5-Bromo-2-chloro-4(1H)-pyridinone
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-2-Chloro-4-Hydroxypyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the stringent requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment. Our quality commitment supports compliance in cGMP and ISO-guided environments for pharmaceutical and industrial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.