Description

2-Chloro-3-Hydroxyisonicotinaldehyde is a versatile and highly functionalized pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique halogenated and hydroxylated structure makes it an invaluable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and metabolic disorders.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and plant growth regulators due to its bioactive pyridine core.
• Ligand Synthesis: Serves as a starting material for creating sophisticated chelating ligands used in catalysis and material science.
• Fine Chemical Production: Employed in the manufacture of dyes, pigments, and other specialty chemicals requiring a functionalized heterocyclic scaffold.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and for exploring new chemical spaces in discovery research.

Basic Information

Product Name	2-Chloro-3-Hydroxyisonicotinaldehyde
CAS No.	1196145-81-9
Molecular Formula	C6H4ClNO2
Molecular Weight	157.55 g/mol
Synonyms	3-Hydroxy-2-chloroisonicotinaldehyde; 2-Chloro-3-hydroxypyridine-4-carbaldehyde; 4-Pyridinecarboxaldehyde, 2-chloro-3-hydroxy-; Isonicotinaldehyde, 2-chloro-3-hydroxy-; 2-Chloro-3-hydroxypyridine-4-carboxaldehyde; 2-Chloro-3-hydroxy-4-formylpyridine; 2-Chloro-3-hydroxypyridine-4-aldehyde
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Hydroxyisonicotinaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability, consistency, and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.