Description

2-Bromo-5-Chloro-4-Hydroxypyridin is a halogenated pyridine derivative, a versatile and high-value building block in advanced organic synthesis. This compound is critical for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs) and agrochemicals, where precise molecular architecture is paramount. It is primarily utilized by the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced herbicides, fungicides, and pesticides with specific modes of action.
• Material Science Research: Used in the synthesis of functionalized ligands for metal-organic frameworks (MOFs) or organic electronic materials.
• Chemical Biology: Employed as a probe or tagging molecule in biochemical research due to its reactive halogen sites.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-Bromo-5-Chloro-4-Hydroxypyridin
CAS No.	1196145-66-0
Molecular Formula	C5H3BrClNO
Molecular Weight	208.44 g/mol
Synonyms	4-Hydroxy-2-bromo-5-chloropyridine; 5-Chloro-2-bromo-4-pyridinol; 2-Bromo-5-chloro-4(1H)-pyridinone; 2-Bromo-5-chloro-4-hydroxypyridine; 5-Chloro-2-bromo-4-hydroxypyridine; 4-Pyridinol, 2-bromo-5-chloro-; 2-Bromo-5-chloro-4-pyridone
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Chloro-4-Hydroxypyridin is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.