Description

3-Ethynyl-2-Methoxypyridine CAS NO 1196145-21-7 is a high-purity, functionalized pyridine derivative characterized by its ethynyl and methoxy substituents, making it a versatile and valuable building block in advanced organic synthesis. This compound is critical for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and specialty materials. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for its role in cross-coupling reactions and as a key synthetic intermediate.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting neurological disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides.
• Material Science: Serves as a monomer or functionalizing agent in the creation of conductive polymers and advanced organic electronic materials.
• Chemical Research: An essential building block in academic and industrial R&D for Suzuki, Sonogashira, and other palladium-catalyzed cross-coupling reactions.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Integral to the multi-step synthesis of complex fine chemicals and specialty additives.

Basic Information

Product Name	3-Ethynyl-2-Methoxypyridine
CAS No.	1196145-21-7
Molecular Formula	C8H7NO
Molecular Weight	133.15 g/mol
Synonyms	2-Methoxy-3-ethynylpyridine; 3-Ethynyl-2-methoxypyridine; 2-Methoxy-3-pyridinylacetylene; 3-Pyridinylacetylene, 2-methoxy-; 2-Methoxypyridin-3-ylacetylene
EINECS	Contact for details

Quality Control

Our 3-Ethynyl-2-Methoxypyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent quality suitable for research and commercial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.