Description

2-Bromo-5-Hydroxyisonicotinaldehyde is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique structure, featuring both bromo and aldehyde functional groups on a pyridine core, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators, leveraging its reactive sites for structural diversification.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis and metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for advanced materials, such as organic semiconductors or metal-organic frameworks (MOFs).
• Chemical Biology Probes: Useful for the design and synthesis of molecular probes and tags for studying biological processes and target engagement.

Basic Information

Product Name	2-Bromo-5-Hydroxyisonicotinaldehyde
CAS No.	1196145-13-7
Molecular Formula	C6H4BrNO2
Molecular Weight	202.01 g/mol
Synonyms	5-Hydroxy-2-bromoisonicotinaldehyde; 2-Bromo-5-hydroxypyridine-4-carbaldehyde; 4-Pyridinecarboxaldehyde, 2-bromo-5-hydroxy-; Isonicotinaldehyde, 2-bromo-5-hydroxy-; 2-Bromo-5-hydroxypyridine-4-carboxaldehyde; 2-Bromo-5-hydroxy-4-formylpyridine; 4-Formyl-2-bromo-5-hydroxypyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-5-Hydroxyisonicotinaldehyde is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to light and oxidation, prolonged exposure to air and light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.