Description

Di-tert-Butyl 3,4-Dihydro-1H-Pyrido[3,4-B]Indole-2,9-Dicarboxylate is a high-purity, advanced pharmaceutical intermediate of significant importance in modern drug discovery. This compound serves as a critical building block for the synthesis of complex heterocyclic molecules, particularly those targeting neurological and oncological pathways. It is primarily required by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex alkaloid-based drug candidates and novel small molecule therapeutics.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Serves as a building block in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs), especially for central nervous system (CNS) targets.
• Chemical Biology: Employed in the development of chemical probes to study biological pathways and protein functions.
• Process Development: Used in route scouting and scale-up studies for the efficient manufacturing of target molecules.
• Academic Research: Utilized in universities and research institutes for exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Item	Details
Product Name	Di-tert-Butyl 3,4-Dihydro-1H-Pyrido[3,4-B]Indole-2,9-Dicarboxylate
CAS No.	1196075-55-4
Molecular Formula	C21H28N2O4
Molecular Weight	372.46 g/mol
Synonyms	Di-tert-butyl 1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole-2,9-dicarboxylate; 2,9-Bis(tert-butoxycarbonyl)-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole; 2,9-Di-Boc-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole; 2,9-Di-tert-butoxycarbonyl-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole; Tetrahydro-β-carboline derivative; 9H-Pyrido[3,4-b]indole-2,9-dicarboxylic acid, 3,4-dihydro-1H-, 2,9-bis(1,1-dimethylethyl) ester
EINECS	Contact for details

Quality Control

Our Di-tert-Butyl 3,4-Dihydro-1H-Pyrido[3,4-B]Indole-2,9-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.