Description

(S)-1-Phenyl-1,2,3,4-Tetrahydroisoquino-Linecarbonylchloride is a high-purity chiral building block and key intermediate in advanced organic synthesis. This compound matters for its critical role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring precise stereochemistry. The product is supplied with a Certificate of Analysis to ensure batch-to-batch consistency and reliability.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.
• Asymmetric Synthesis: Used as a precursor for constructing complex, enantiomerically pure molecules in medicinal chemistry and process development.
• Agrochemical Research: Serves as a building block for developing new chiral active ingredients with specific biological activity.
• Catalyst & Ligand Development: Employed in the synthesis of novel chiral catalysts and ligands for asymmetric transformations.
• Academic & R&D Laboratories: Utilized in methodological studies and the discovery of new synthetic routes in organic chemistry.
• Fine Chemical Production: Integral to the manufacture of high-value, specialty chemicals where stereochemical purity is paramount.

Basic Information

Item	Details
Product Name	(S)-1-Phenyl-1,2,3,4-Tetrahydroisoquino-Linecarbonylchloride
CAS No.	1195949-26-8
Molecular Formula	C16H14ClNO
Molecular Weight	271.74 g/mol
Synonyms	(S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline-1-carbonyl chloride; (S)-N-(1-Phenyl-1,2,3,4-tetrahydroisoquinolin-1-yl)formyl chloride; (S)-1-Phenyl-3,4-dihydroisoquinoline-1(2H)-carbonyl chloride; (S)-1,2,3,4-Tetrahydro-1-phenylisoquinoline-1-carbonyl chloride; (S)-Tetrahydroisoquinolinecarbonyl chloride derivative
EINECS	Contact for details

Quality Control

Our (S)-1-Phenyl-1,2,3,4-Tetrahydroisoquino-Linecarbonylchloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for research and production use. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and performance consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.