Description

1H-Pyrrolo[2,3-B]Pyridine-3-Carboxylic Acid, Ethyl Ester is a high-value heterocyclic building block, specifically an ethyl ester derivative of a fused pyrrolopyridine carboxylic acid. This compound is critical for its role as a versatile synthetic intermediate in advanced organic synthesis and pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides due to its bioactive heterocyclic core.
• Material Science: Acts as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for biological target validation.
• Academic & Contract Research: Essential for methodological development and novel synthetic route exploration in university and CRO laboratories.
• Custom Synthesis: A starting material for the contract manufacturing of bespoke fine chemicals and advanced intermediates.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-3-Carboxylic Acid, Ethyl Ester
CAS No.	1195622-96-8
Molecular Formula	C10H10N2O2
Molecular Weight	190.20 g/mol
Synonyms	Ethyl 1H-pyrrolo[2,3-b]pyridine-3-carboxylate; 1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid ethyl ester; 7-Azaindole-3-carboxylic acid ethyl ester; Ethyl 7-azaindole-3-carboxylate; 3-Carbethoxy-7-azaindole; 1H-7-Azaindole-3-carboxylic acid, ethyl ester; Ethyl 1H-7-azaindole-3-carboxylate
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-3-Carboxylic Acid, Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong alkalis and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.