Description

5-Bromo-1-Cyclopropylpyridin-2(1H)-One is a high-purity, advanced pharmaceutical intermediate featuring a unique halogenated pyridinone scaffold. This compound is valued for its role as a versatile building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in areas requiring complex heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides due to its bioactive pyridinone core.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization, including cross-coupling reactions like Suzuki or Buchwald-Hartwig amination.
• Material Science: Potential monomer or additive in the research of specialty polymers and advanced organic materials.
• Academic & Contract Research: Employed in university and CRO laboratories for method development and exploratory chemistry projects.

Basic Information

Product Name	5-Bromo-1-Cyclopropylpyridin-2(1H)-One
CAS No.	1193334-67-6
Molecular Formula	C8H8BrNO
Molecular Weight	214.06 g/mol
Synonyms	5-Bromo-1-cyclopropyl-2(1H)-pyridinone; 5-Bromo-1-cyclopropylpyridin-2(1H)-one; 2(1H)-Pyridinone, 5-bromo-1-cyclopropyl-; 5-Bromo-1-cyclopropyl-1,2-dihydropyridin-2-one; 5-Bromo-1-cyclopropyl-2-hydroxypyridine; 1-Cyclopropyl-5-bromopyridin-2(1H)-one
EINECS	Contact for details

Quality Control

Our 5-Bromo-1-Cyclopropylpyridin-2(1H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.