Description

5-Bromo-2-(Bromomethyl)Pyrimidine is a versatile and highly reactive halogenated pyrimidine building block, essential for advanced organic synthesis. Its dual bromine functionality makes it a critical intermediate for constructing complex molecular architectures through cross-coupling and nucleophilic substitution reactions. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its pyrimidine core.
• Material Science: Serves as a building block for creating functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Research: Employed in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries.
• Cross-Coupling Reactions: The bromine atoms are excellent handles for Suzuki, Stille, and Buchwald-Hartwig amination reactions to introduce the pyrimidine moiety.
• Nucleic Acid Chemistry: Useful in the modification of nucleosides and the synthesis of non-natural nucleotide analogs.

Basic Information

Product Name	5-Bromo-2-(Bromomethyl)Pyrimidine
CAS No.	1193116-74-3
Molecular Formula	C5H4Br2N2
Molecular Weight	251.90 g/mol
Synonyms	2-(Bromomethyl)-5-bromopyrimidine; 5-Bromo-2-(bromomethyl)pyrimidine; Pyrimidine, 5-bromo-2-(bromomethyl)-; 5-Bromo-2-bromomethylpyrimidine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-(Bromomethyl)Pyrimidine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and production use. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques. Our quality management system is designed to meet the stringent requirements of our global customer base in the pharmaceutical and fine chemical sectors.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.