Description

3-(4-Fluorophenyl)Picolinic Acid is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, combining a picolinic acid scaffold with a fluorinated phenyl ring, which is critical for modulating the physicochemical and biological properties of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it serves as a key precursor for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, where the fluorine atom enhances bioavailability and environmental stability.
• Ligand Synthesis for Catalysis: Serves as a precursor for creating sophisticated chelating ligands used in transition metal catalysis for asymmetric synthesis.
• Material Science Precursor: Employed in the research of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its conjugated system.
• Chemical Biology Probe Development: Utilized to synthesize molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards for client-specific molecules.

Basic Information

Product Name	3-(4-Fluorophenyl)Picolinic Acid
CAS No.	1192608-90-4
Molecular Formula	C₁₂H₈FNO₂
Molecular Weight	217.20 g/mol
Synonyms	2-(4-Fluorophenyl)pyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 2-(4-fluorophenyl)-; 2-(4-Fluorophenyl)nicotinic Acid; 3-Carboxy-2-(4-fluorophenyl)pyridine; 1192608-90-4; 2-(p-Fluorophenyl)nicotinic Acid; 3-(4-Fluorophenyl)-2-pyridinecarboxylic Acid
EINECS	Contact for details

Quality Control

Every batch of 3-(4-Fluorophenyl)Picolinic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and scale-up. A detailed Certificate of Analysis (COA), including HPLC purity, identity confirmation (IR, NMR), and impurity profile, is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.