Description

5-Cyano-3-Nitro-7-Azaindole is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular architecture, featuring cyano and nitro substituents on an azaindole core, makes it a versatile precursor for constructing complex pharmacophores and functional materials. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel small-molecule therapeutics, agrochemicals, and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of kinase inhibitors, anticancer agents, and other biologically active compounds.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a building block for organic semiconductors, dyes, and photoactive materials.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for target validation and mechanistic studies.
• Academic & Contract Research: Essential for methodological development in organic chemistry and medicinal chemistry programs.
• Custom Synthesis: A starting material for the contract manufacturing of proprietary compounds and advanced intermediates.

Basic Information

Product Name	5-Cyano-3-Nitro-7-Azaindole
CAS No.	1190322-60-1
Molecular Formula	C8H4N4O2
Molecular Weight	188.15 g/mol
Synonyms	7-Azaindole-5-carbonitrile, 3-nitro-; 3-Nitro-1H-pyrrolo[2,3-b]pyridine-5-carbonitrile; 3-Nitro-5-cyano-7-azaindole; 3-Nitro-7-azaindole-5-carbonitrile; 1H-Pyrrolo[2,3-b]pyridine-5-carbonitrile, 3-nitro-; 5-Cyano-3-nitro-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 5-Cyano-3-Nitro-7-Azaindole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, NMR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive nature and potential for oxidation, it is recommended to handle under an inert atmosphere for long-term storage and to minimize repeated exposure to air.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.