Description

3-Bromo-4-Fluoro-7-Azaindole is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines halogen substituents with a nitrogen-rich azaindole scaffold, enabling precise structural modifications and the introduction of key pharmacophores. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents, leveraging the 7-azaindole core's bioisosteric properties.
• Agrochemical Research: Used in the development of new herbicides and fungicides, where the halogenated azaindole structure can confer specific biological activity.
• Material Science: Serves as a building block for creating specialized organic ligands and functional polymers with tailored electronic properties.
• Chemical Biology: Employed as a probe or labeling reagent due to its reactive bromo and fluoro sites for bioconjugation and structure-activity relationship (SAR) studies.
• Academic & Contract Research: Essential for methodological development in cross-coupling reactions and heterocyclic chemistry within R&D laboratories.

Basic Information

Product Name	3-Bromo-4-Fluoro-7-Azaindole
CAS No.	1190320-00-3
Molecular Formula	C7H4BrFN2
Molecular Weight	215.02 g/mol
Synonyms	3-Bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridine; 4-Fluoro-3-bromo-7-azaindole; 4-Fluoro-3-bromo-1H-pyrrolo[2,3-b]pyridine; 3-Bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 3-bromo-4-fluoro-; 3-Bromo-4-fluoro-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-4-Fluoro-7-Azaindole is manufactured under strict quality management protocols. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and process chemistry. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profile via techniques such as HPLC, NMR, and LC-MS is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC / NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC Area %)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.