Description

4-Bromo-1H-Pyrrolo[2,3-C]Pyridin-2(3H)-One is a high-value brominated heterocyclic building block, specifically a functionalized pyrrolopyridinone derivative. This compound is critical for medicinal chemistry research and development, serving as a versatile scaffold for constructing novel bioactive molecules. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of kinase inhibitors and other targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for targeted cancer therapies.
• Kinase Inhibitor Scaffold: Serves as a core structural element for designing and synthesizing potent and selective kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs in academic and industrial labs.
• Bioconjugation & Probe Development: The bromo substituent allows for further functionalization via cross-coupling reactions, useful for creating chemical probes.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals for advanced applications.

Basic Information

Product Name	4-Bromo-1H-Pyrrolo[2,3-C]Pyridin-2(3H)-One
CAS No.	1190318-93-4
Molecular Formula	C7H5BrN2O
Molecular Weight	213.03 g/mol
Synonyms	4-Bromo-1,3-dihydro-2H-pyrrolo[2,3-c]pyridin-2-one; 4-Bromo-2,3-dihydro-1H-pyrrolo[2,3-c]pyridin-2-one; 4-Bromo-2-oxo-2,3-dihydro-1H-pyrrolo[2,3-c]pyridine; 4-Bromo-1H-pyrrolo[2,3-c]pyridin-2(3H)-one; 4-Bromopyrrolo[2,3-c]pyridin-2-one
EINECS	Contact for details

Quality Control

Our 4-Bromo-1H-Pyrrolo[2,3-C]Pyridin-2(3H)-One is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.