Description

3-Bromo-4-Azaindole-5-Carboxylic Acid Methyl Ester is a high-purity, versatile heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its unique molecular scaffold, which serves as a critical intermediate in the development of novel pharmacologically active molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the synthesis of kinase inhibitors and other targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of small molecule drug candidates, especially kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel therapeutic targets.
• Chemical Biology Probes: Serves as a scaffold for developing tool compounds to study biological pathways and protein function.
• Agrochemical Research: Potential intermediate in the discovery of new active ingredients for crop protection.
• Academic Research: Employed in organic methodology development and the synthesis of complex heterocyclic libraries.

Basic Information

Product Name	3-Bromo-4-Azaindole-5-Carboxylic Acid Methyl Ester
CAS No.	1190318-72-9
Molecular Formula	C9H7BrN2O2
Molecular Weight	255.07 g/mol
Synonyms	Methyl 3-bromo-1H-pyrrolo[2,3-b]pyridine-5-carboxylate; 3-Bromo-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid methyl ester; 3-Bromo-4-aza-1H-indole-5-carboxylic acid methyl ester; 3-Bromo-4-azaindole-5-methyl carboxylate; 1H-Pyrrolo[2,3-b]pyridine-5-carboxylic acid, 3-bromo-, methyl ester; 3-Bromo-4-azaindole-5-carboxylate methyl ester
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Azaindole-5-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and industry best practices for research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder/crystalline solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.