Description

4-Methyl-3-Nitro-7-Azaindole-5-Carboxylic Acid Methyl Ester is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters because it serves as a critical precursor in the development of novel pharmaceutical agents, particularly kinase inhibitors and other targeted therapeutics. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of protein kinase inhibitors and other biologically active molecules.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies for new drug candidates.
• Chemical Biology Probes: Serves as a scaffold for developing tool compounds to study enzyme function and cellular pathways.
• Process Chemistry: Employed in route scouting and scale-up synthesis for Active Pharmaceutical Ingredients (APIs).
• Agrochemical Research: Potential building block for the development of new crop protection agents.
• Academic Research: Used in universities and institutes for novel heterocyclic chemistry methodology development.

Basic Information

Item	Detail
Product Name	4-Methyl-3-Nitro-7-Azaindole-5-Carboxylic Acid Methyl Ester
CAS No.	1190316-46-1
Molecular Formula	C10H9N3O4
Molecular Weight	235.20 g/mol
Synonyms	Methyl 4-Methyl-3-nitro-1H-pyrrolo[2,3-b]pyridine-5-carboxylate; 3-Nitro-4-methyl-7-azaindole-5-carboxylic acid methyl ester; 1H-Pyrrolo[2,3-b]pyridine-5-carboxylic acid, 4-methyl-3-nitro-, methyl ester; 7-Azaindole-5-carboxylic acid, 4-methyl-3-nitro-, methyl ester
EINECS	Contact for details

Quality Control

Our 4-Methyl-3-Nitro-7-Azaindole-5-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.