Description

4-Chloro-3-Nitro-5-Azaindole is a high-value, multi-functional heterocyclic building block used in advanced organic synthesis. This compound is critical for medicinal chemistry research and the development of novel pharmaceutical agents, particularly kinase inhibitors. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted small molecule drugs, especially protein kinase inhibitors.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR).
• Agrochemical Development: Serves as a building block for creating new active ingredients with herbicidal or pesticidal properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and cellular pathways.
• Material Science: Potential monomer or precursor for specialty polymers and advanced organic electronic materials.

Basic Information

Product Name	4-Chloro-3-Nitro-5-Azaindole
CAS No.	1190316-31-4
Molecular Formula	C7H4ClN3O2
Molecular Weight	197.58 g/mol
Synonyms	4-Chloro-3-nitro-1H-pyrrolo[3,2-b]pyridine; 3-Nitro-4-chloro-5-azaindole; 4-Chloro-3-nitro-5-aza-1H-indole; 1H-Pyrrolo[3,2-b]pyridine, 4-chloro-3-nitro-; 5-Azaindole, 4-chloro-3-nitro-; 4-Chloro-3-nitropyrrolo[3,2-b]pyridine
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Nitro-5-Azaindole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.