Description

6-Cyano-5-Fluoro-7-Azaindole is a high-value, multi-functional heterocyclic building block essential for modern pharmaceutical and agrochemical research. Its unique azaindole core, functionalized with cyano and fluoro groups, makes it a critical intermediate for constructing complex molecules with targeted biological activity. This compound is primarily utilized by R&D chemists and process development scientists in the life sciences sector for the synthesis of novel active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key scaffold in the synthesis of kinase inhibitors and other small-molecule therapeutics targeting oncology, inflammation, and central nervous system (CNS) disorders.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Chemical Biology & Probe Development: Used in the creation of molecular probes and tool compounds for studying enzyme function and biological pathways.
• Material Science Precursor: Potential intermediate for the synthesis of specialized organic electronic materials and ligands for catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects at various scales, from milligram to kilogram.

Basic Information

Product Name	6-Cyano-5-Fluoro-7-Azaindole
CAS No.	1190316-08-5
Molecular Formula	C8H4FN3
Molecular Weight	161.14 g/mol
Synonyms	5-Fluoro-7-azaindole-6-carbonitrile; 5-Fluoro-1H-pyrrolo[2,3-b]pyridine-6-carbonitrile; 6-Cyano-5-fluoro-1H-pyrrolo[2,3-b]pyridine; 5-Fluoro-6-cyano-7-azaindole; 1H-Pyrrolo[2,3-b]pyridine-6-carbonitrile, 5-fluoro-
EINECS	Contact for details

Quality Control

Our 6-Cyano-5-Fluoro-7-Azaindole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP principles and regulatory compliance (REACH, FDA DMF support available) ensures the material is suitable for advanced research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.