Description

3-Amino-6-Cyano-4-Azaindole is a high-purity, advanced pharmaceutical intermediate belonging to the azaindole class of heterocyclic compounds. This specialized building block is critical for the research and development of novel, small-molecule therapeutics targeting a range of diseases. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology sectors. The compound's unique fused-ring structure with multiple functional handles makes it a valuable scaffold for constructing complex molecular architectures in drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of targeted kinase inhibitors for oncology and inflammatory disease research.
• Medicinal Chemistry Scaffold: Used as a core structural element for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Biochemical Research: Employed in the development of chemical probes to study specific enzyme functions and biological pathways.
• Process Chemistry: Utilized in route scouting and optimization for the scalable production of active pharmaceutical ingredients (APIs).
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and development services for the pharmaceutical industry.

Basic Information

Product Name	3-Amino-6-Cyano-4-Azaindole
CAS No.	1190312-49-2
Molecular Formula	C8H6N4
Molecular Weight	158.16 g/mol
Synonyms	4-Azaindole-3-amine, 6-cyano-; 6-Cyano-1H-pyrrolo[3,2-c]pyridin-3-amine; 3-Amino-6-cyano-1H-pyrrolo[3,2-c]pyridine; 6-Cyano-3-amino-4-azaindole; 3-Amino-6-cyano-4-aza-indole; 1H-Pyrrolo[3,2-c]pyridine-3-amine, 6-cyano-
EINECS	Contact for details

Quality Control

Every batch of 3-Amino-6-Cyano-4-Azaindole is manufactured under a strict quality management system and undergoes comprehensive analytical testing. We provide full traceability and ensure compliance with current industry standards for advanced pharmaceutical intermediates. A detailed Certificate of Analysis (COA), including results from HPLC, NMR, and MS, is supplied with each shipment to guarantee identity, purity, and consistency for your critical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive and hygroscopic; therefore, containers should be kept sealed under an inert atmosphere when not in use to maintain long-term stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.