Description

3-Nitro-4-Azaindole-5-Carboxylic Acid Methyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its nitro-substituted azaindole core. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of novel, targeted therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potent kinase inhibitors for oncology and anti-inflammatory applications.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Used in the development of assay probes to study specific enzyme pathways and biological mechanisms.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the cGMP production of active pharmaceutical ingredients (APIs).
• Academic Research: Employed in university and institutional labs for exploratory synthetic chemistry and novel heterocycle development.

Basic Information

Product Name	3-Nitro-4-Azaindole-5-Carboxylic Acid Methyl Ester
CAS No.	1190310-77-0
Molecular Formula	C9H7N3O4
Molecular Weight	221.17 g/mol
Synonyms	Methyl 3-nitro-1H-pyrrolo[3,2-b]pyridine-5-carboxylate; 1H-Pyrrolo[3,2-b]pyridine-5-carboxylic acid, 3-nitro-, methyl ester; 3-Nitro-1H-pyrrolo[3,2-b]pyridine-5-carboxylic acid methyl ester; 4-Azaindole-5-carboxylic acid, 3-nitro-, methyl ester; 3-Nitro-4-aza-indole-5-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 3-Nitro-4-Azaindole-5-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.