Description

3-Formyl-7-Azaindole-5-Carboxylic Acid Methyl Ester is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its versatile reactive sites—the formyl and ester groups—which enable precise derivatization for creating complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel kinase inhibitors and other biologically active small molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potent kinase inhibitors targeting various oncology and inflammatory disease pathways.
• Agrochemical Research: Used to construct novel heterocyclic scaffolds for the development of new herbicides and fungicides.
• Chemical Biology Probe Development: Serves as a versatile handle for creating fluorescent tags or affinity probes to study protein-ligand interactions.
• Material Science: Potential building block for organic electronic materials and metal-organic frameworks (MOFs) due to its conjugated azaindole core and coordinating sites.
• Academic & Contract Research: Employed in methodological studies and discovery chemistry for novel heterocycle formation and cross-coupling reactions.

Basic Information

Product Name	3-Formyl-7-Azaindole-5-Carboxylic Acid Methyl Ester
CAS No.	1190309-80-8
Molecular Formula	C10H8N2O3
Molecular Weight	204.18 g/mol
Synonyms	Methyl 3-formyl-1H-pyrrolo[2,3-b]pyridine-5-carboxylate; 1H-Pyrrolo[2,3-b]pyridine-5-carboxylic acid, 3-formyl-, methyl ester; 3-Formyl-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid methyl ester; 7-Azaindole-5-carboxylic acid, 3-formyl-, methyl ester; 3-Formyl-7-aza-indole-5-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 3-Formyl-7-Azaindole-5-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to prevent oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.