Description

3-Bromo-5-Fluoro-1H-Pyrrolo[2,3-B]Pyridine is a high-value, multi-functional heterocyclic building block essential for modern organic synthesis. Its core value lies in enabling the rapid construction of complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). This compound is critically needed by research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors for creating next-generation small molecule therapeutics and functional compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted therapies, leveraging the pyrrolopyridine scaffold's bioisosteric properties.
• Agrochemical Research: Used in the development of new herbicides and fungicides, where the halogenated heterocycle can impart unique biological activity.
• Material Science: Serves as a building block for organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Biology: Employed in the design of molecular probes and tool compounds for studying biological pathways and target engagement.
• Medicinal Chemistry: Facilitates structure-activity relationship (SAR) studies and lead optimization campaigns due to its versatile halogen handles for further functionalization.
• Custom Synthesis: A fundamental starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.

Basic Information

Product Name	3-Bromo-5-Fluoro-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	1190309-71-7
Molecular Formula	C7H4BrFN2
Molecular Weight	215.02 g/mol
Synonyms	3-Bromo-5-fluoro-1H-pyrrolo[2,3-b]pyridine; 5-Fluoro-3-bromo-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 3-bromo-5-fluoro-; 3-Bromo-5-fluoro-7-azaindole; 5-Fluoro-3-bromo-7-azaindole; 3-Bromo-5-fluoro-1H-7-azaindole
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Fluoro-1H-Pyrrolo[2,3-B]Pyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) detailing all specifications is available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect from moisture and contamination.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.